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KMID : 0854720090290040289
Korean Journal of Asthma, Allergy and Clinical Immunology
2009 Volume.29 No. 4 p.289 ~ p.292
A Case of Diclofenac-induced Angioedema Requiring Emergency Tracheostomy
Park Se-Young

Na Dong-Jip
Ko Bong-Suk
Kim Jung-Ho
Lee Min-Kyung
Kim Si-Bum
Cho Yong-Soo
Lee Yang-Deok
Cho Yong-Seon
Han Min-Soo
Lim Mi-Kyung
Abstract
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed, which have an inflammation as well as an analgestic effects reducing effect. However, NSAIDs also have many potential adverse reactions, and NSAID- induced angioedema occurs infrequently. Angioedema is characterized by an acute-onset non-pitting edema of the skin, mucosa and subcutaneous tissue. With a particular predilection for the head and neck area including the face, lips, tongue and pharynx, angioedema may be fatal by causing acute upper airway obstruction. We report a case of diclofenac-induced angioedema, involving the soft palate, uvula, tongue and pharynx, complicated by impending upper airway obstruction requiring emergency tracheostomy. This is the first reported case, to our knowledge, of diclofenac- induced angioedema in Korea.
KEYWORD
Angioedema, Diclofenac, Tracheostomy
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