KMID : 0854720090290040289
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Korean Journal of Asthma, Allergy and Clinical Immunology 2009 Volume.29 No. 4 p.289 ~ p.292
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A Case of Diclofenac-induced Angioedema Requiring Emergency Tracheostomy
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Park Se-Young
Na Dong-Jip Ko Bong-Suk Kim Jung-Ho Lee Min-Kyung Kim Si-Bum Cho Yong-Soo Lee Yang-Deok Cho Yong-Seon Han Min-Soo Lim Mi-Kyung
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Abstract
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Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed, which have an inflammation as well as an analgestic effects reducing effect. However, NSAIDs also have many potential adverse reactions, and NSAID- induced angioedema occurs infrequently. Angioedema is characterized by an acute-onset non-pitting edema of the skin, mucosa and subcutaneous tissue. With a particular predilection for the head and neck area including the face, lips, tongue and pharynx, angioedema may be fatal by causing acute upper airway obstruction. We report a case of diclofenac-induced angioedema, involving the soft palate, uvula, tongue and pharynx, complicated by impending upper airway obstruction requiring emergency tracheostomy. This is the first reported case, to our knowledge, of diclofenac- induced angioedema in Korea.
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KEYWORD
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Angioedema, Diclofenac, Tracheostomy
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